SynthID Bio Watermarks AI-Generated Proteins Without Losing Function

On September 30, 2026 Google DeepMind unveiled SynthID Bio, a system that embeds an imperceptible watermark into AI-designed proteins while preserving their biological activity. It works by subtly influencing amino-acid choice or atomic coordinates, and lab tests show watermarked binders for VEGF-A, SARS-CoV-2 spike RBD, and PD-L1 match unmarked counterparts in hit rate, affinity, and sequence diversity.